Most patients asking about Bellafill have already been through the cycle — temporary fillers every six to twelve months. Bellafill is the only FDA-approved semi-permanent dermal filler, delivering results that hold up to five years.
At Desert Bloom in Scottsdale, Dr. Natalya Borakowski, NMD offers complimentary Bellafill consultations to help you decide if this long-lasting option fits your goals.
What: Non-surgical injectable dermal filler at Desert Bloom using PMMA microspheres + bovine collagen
Treats: Nasolabial folds, acne scars (FDA-approved), temples, back of hands, marionette lines, wrinkles
Results: Up to five years — the longest of any injectable filler
Downtime: Minimal — most patients resume normal activities within 1–2 days
Consultation: Complimentary
Bellafill is one of several dermal filler treatments at Desert Bloom, alongside Sculptra, Radiesse, and lip augmentation.
Bellafill is an injectable dermal filler composed of 20% PMMA microspheres suspended in 80% bovine collagen gel. Unlike temporary injectables that dissolve within months, Bellafill works in two phases: the collagen carrier provides immediate volume, while the PMMA microspheres act as a permanent scaffold stimulating your own collagen production.

Bellafill is FDA approved for two indications — nasolabial folds (since October 2006, originally marketed as ArteFill) and moderate-to-severe atrophic acne scars on the cheeks (since January 2015). It remains the first and only filler with FDA approval for acne scars.
After Bellafill injections, the bovine collagen carrier begins to absorb naturally over one to three months. What remains are the PMMA microspheres — tiny, smooth, non-resorbable spheres that your body cannot break down. Your body’s collagen-producing cells (fibroblasts) migrate to the microspheres and create a new collagen matrix around them, helping to lift treated areas and build a lasting structural foundation.

The result is your own collagen providing the structure — not just a gel that dissolves. That is why Bellafill can deliver results lasting up to five years — longer than most other fillers. This non-surgical procedure achieves smoothing of wrinkles and lines while stimulating natural collagen to enhance your appearance over time.
Bellafill treatment addresses both on-label and off-label concerns, helping patients achieve durable results for a range of facial areas. The table below outlines the areas most commonly treated with Bellafill injections.
| Treatment Area | FDA Status | Notes |
|---|---|---|
| Nasolabial folds (smile lines) | On-label | Moderate to severe lines from nose to mouth — treat nasolabial folds. Typically 2–3 syringes total. |
| Acne scars (cheeks) | On-label | Moderate to severe atrophic, distensible scars — acne scar correction. Typically 1 syringe is enough. |
| Temples | Off-label | Hollow temple correction |
| Back of Hands | Off-label | Volume restoration for aging hands |
| Marionette lines | Off-label | Lines running from mouth corners downward |
Important: Bellafill is NEVER used under the eyes (tear trough) or in the lips at Desert Bloom due to the elevated risk of complications with a non-reversible injectable in these areas.
Bellafill is the only filler with FDA approval for acne scars — a distinction no other injectable holds. The acne scar trial showed 64% of treated patients responded at six months versus 33% in the control group (FDA PMA P020012S009). Bellafill does not provide significant volume like traditional HA fillers, which is why it has special applications in areas where collagen stimulation, smoothing, and long-term structural support matter more than immediate volume.

For patients who have already tried wrinkle-smoothing injectables and want a treatment that doesn’t need replacing, Bellafill can improve and enhance outcomes that temporary fillers cannot sustain.
Off-label uses require an experienced provider with detailed knowledge of facial anatomy and Bellafill’s permanent nature. The treated area must be carefully assessed to achieve the best possible results. Your provider will work with you to determine the right approach — helping to provide a safe, effective plan that fits your anatomy and your goals.
Bellafill results last up to five years — making it the most long-lasting injectable filler available. The FDA post-approval study followed 1,008 patients across 23 centers and found an 87% retention rate at five years, with 83% patient satisfaction (Cohen et al., 2015). A separate review of 212 treated patients over four years confirmed consistent safety and satisfaction outcomes (Solomon et al., 2021).
So is Bellafill permanent? Let’s be clear: the PMMA microspheres themselves persist indefinitely — they are non-resorbable. But the aesthetic result evolves as natural aging continues. As patients age, facial volume shifts, skin quality changes, and gravity does not pause. That is why “semi-permanent” is more accurate than “permanent.” Touch-ups are not commonly needed, though individual results vary because the PMMA component creates a permanent scaffold stimulating collagen. Some patients may choose to repeat the procedure on the same treated area — usually temples or hands — after approximately 12 months, once the bovine collagen carrier has been fully absorbed and replaced by natural collagen, helping to lift and improve the face over time.
For patients tired of scheduling filler injections every six to twelve months, Bellafill offers a fundamentally different timeline — with results that can hold for years rather than months.

Bellafill, Sculptra biostimulator, and Radiesse are all biostimulators — injectables that trigger your body’s collagen production rather than simply adding gel. The key differences are duration, mechanism, and candidacy.
| Feature | Bellafill | Sculptra | Radiesse |
|---|---|---|---|
| Duration | 5+ years | 2–3 years | 12–18 months |
| Immediate result | Yes | No (gradual) | Yes |
| FDA acne scar approval | Yes | No | No |
| Reversible | No | Degrades naturally | Degrades naturally |
| Typical sessions | 1–2 | 2–4 | 1 per year |
| Skin test required | Only if patient doesn’t eat beef | No | No |
Unlike temporary fillers such as Juvederm or Restylane — which dissolve within six to eighteen months — Bellafill’s PMMA microspheres do not break down. That permanence is a benefit for the right candidate, helping to create durable improvement in wrinkles and volume, and a reason for careful patient selection for everyone else. Patients who currently use Botox or temporary fillers to address age-related lines often find that Bellafill provides a more stable structural foundation, reducing how often they need injections overall.
Explore other dermal fillers to compare what fits your goals. For patients who prefer a fully natural approach, PRP Biofiller uses your own platelet-rich plasma as an injectable — no synthetic material at all.
Bellafill cost is $800 per syringe (0.8 mL) in Scottsdale. A full box of 5 syringes is available for $3,500 when paid upfront — a $500 savings. The number of syringes depends on the treated area and depth of correction: acne scars typically require 1 syringe, while nasolabial folds usually need 2–3 syringes total. We determine the exact plan during your consultation.
Because Bellafill results last up to five years, the procedure can be more cost-effective over time than fillers requiring annual retreatment. We are happy to discuss cost comparisons during your consultation — our job is to make sure the treatment is right for your anatomy first.
View full treatment pricing or schedule a complimentary Bellafill consultation to discuss your specific needs. A skin test is required for some patients, as noted below. Bellafill offers a non-surgical option with results that may not need replacing as frequently as temporary fillers — and it can provide significant cost savings compared to repeating temporary filler injections year after year.
Bellafill is FDA approved with over 650,000 syringes tracked in post-marketing surveillance from 2007 to 2017 (Hanke et al., 2019). Common side effects of Bellafill injections include redness, swelling, and bruising at the injection site, typically resolving within days. Most patients resume normal activities within 1–2 days — a key advantage of this non-surgical procedure. This experience is similar across age groups, though individual recovery varies, and patients of all skin types and age backgrounds have been successfully treated in clinical studies.
The post-approval study reported a granuloma incidence of 1.7% over five years; the broader surveillance data showed a rate of 0.002% per syringe. Rare but serious complications include granuloma formation and vascular occlusion. Dr. Borakowski follows strict injection protocols and monitors patients at follow-up appointments.
Bellafill cannot be dissolved like HA fillers. If a problem arises, surgical excision is the only removal option. This irreversibility makes provider selection and a thorough consultation especially important. It is not a procedure to rush into — and we will not rush you.
You may be a good candidate if you are:
Candidacy is determined during a complimentary consultation with Dr. Natalya Borakowski, NMD. Not every patient is the right candidate for a semi-permanent filler — and your provider will tell you honestly if another approach, such as temporary injectables or Botox, makes more sense for your goals. That honesty is what differentiates Desert Bloom Skincare in Scottsdale.
Dr. Natalya Borakowski, NMD founded Desert Bloom Skincare with a clinical aesthetics approach grounded in holistic assessment and ethical aesthetics. With 17 years in aesthetic medicine and a naturopathic doctorate, every Bellafill treatment plan starts with careful evaluation of your anatomy, goals, and whether this semi-permanent filler is genuinely the right fit.


“Bellafill is a permanent dermal filler solution, a great option for aging thinning skin and for management of rolling acne scars. Due to a unique collagen stimulation mechanism, this filler produces permanent reduction of acne scars and long-term improvement of lines and wrinkles.”
Schedule a complimentary Bellafill consultation at Desert Bloom Skincare. Dr. Borakowski will evaluate your concerns, discuss goals, and give you an honest recommendation — no pressure, no obligation.
Desert Bloom Skincare
10752 N 89th Place, Suite 122B, Scottsdale, AZ 85260
← Explore all dermal filler treatments at Desert Bloom
Individual results vary. Bellafill treatment requires a complimentary consultation and may require a skin test for patients who do not consume beef. Off-label uses mentioned on this page are for educational purposes only and reflect common clinical practice; they are not FDA-approved indications. All medical procedures carry risks. Consult with a qualified provider to determine if Bellafill is appropriate for your specific concerns and medical history.
Desert Bloom Skincare Center offers personalized skincare consultation to help you achieve a flawless and radiant complexion. Book your appointment today and let our expert team of skincare professionals address your specific concerns and help you reach your skincare goals.
Phone:(480) 567-8180
E-mail:info@desertbloomskincare.com
Get Directions →Desert Bloom Skincare is conveniently located in the Shea Corridor of North Scottsdale, within Edwards Professional Park I — minutes from HonorHealth Scottsdale Shea Medical Center and the Mayo Clinic Scottsdale Campus.
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